[Designated 2nd-Class OTC Drug] Estac EX Neo 36 tablets

Relief of cold symptoms (sore throat, fever, runny nose, stuffy nose, cough, phlegm, sneezing, chills, headache, joint pain, muscle pain)

[Usage/Dosage] Take the following dose three times a day, preferably within 30 minutes after meals, with water or lukewarm water. [Age: 1 dose] Adults (15 years and older): 2 tablets Under 15 years of age: Do not take [Precautions related to usage and administration] (1) Please strictly follow the directions and dosage. (2) How to take out the tablet Press the convex part of the PTP sheet containing the tablet firmly with your fingertips to break the aluminum foil on the back, take it out and drink. (If you accidentally swallow it whole, it may pierce the esophageal mucosa or cause an unexpected accident.)

[Ingredient amount] In 6 tablets (adult daily dose): ibuprofen 600 mg, isopropamide iodide 6 mg, chlorpheniramine maleate 7.5 mg, ambroxol hydrochloride 45 mg, dihydrocodeine phosphate 24 mg, dl-methylephedrine hydrochloride 60 mg, anhydrous caffeine 75 mg, magnesium oxide 300 mg [Additives] Silicic anhydride, cellulose, lactose, hydroxypropyl cellulose, hypromellose, crospovidone, macrogol, D-mannitol, Mg stearate, talc, titanium oxide, corn starch, polyvinyl alcohol/acrylic acid/methyl methacrylate copolymer

[Precautions for use] ■What not to do (If you do not follow these guidelines, your current symptoms may worsen, or you may be more likely to experience side effects or accidents.) (If you do not follow these precautions, your current symptoms may worsen or side effects or accidents may occur more easily.) 1. The following people should not take this product: (1) Persons who have had allergic symptoms due to this drug or its ingredients. (2) People who have had asthma while taking this drug or other cold medicines or antipyretic analgesics. (3) Children under 15 years of age. (4) Pregnant women within 12 weeks of due date. (5) Persons receiving treatment or medication for the following illnesses at a medical institution. Stomach/duodenal ulcer, blood disease, liver disease, kidney disease, heart disease, high blood pressure, people taking zidovudine (Retrovir) 2. Do not use any of the following medicines while taking this drug: Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, oral medicines containing antihistamines (oral medicines for rhinitis, motion sickness medicines, allergy medicines, hypnotic sedatives, etc.), gastrointestinal analgesics and antispasmodics. 3. Do not drive a vehicle or operate machinery after taking this medicine. (Symptoms such as drowsiness, blurred vision, and abnormal glare may occur.) 4. Do not take this drug if you are breastfeeding, or avoid breastfeeding if you are taking this drug. 5. Do not drink alcohol before or after taking the drug 6. Do not take for more than 5 days ■To consult 1. The following people should consult a doctor, pharmacist, or registered salesperson before taking the drug. (1) Persons receiving treatment from a doctor or dentist. (2) Pregnant women or people who appear to be pregnant. (3) Elderly people. (4) People who have had allergic symptoms due to drugs, etc. (5) People with the following symptoms. High fever, difficulty urinating (6) Persons who have received the following diagnosis. Thyroid dysfunction, diabetes, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, bronchial asthma, respiratory dysfunction, obstructive sleep apnea syndrome, obesity (7) Persons who have had the following diseases. Stomach/duodenal ulcer, ulcerative colitis, Crohn's disease, blood disease, liver disease, kidney disease 2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor, pharmacist, or registered salesperson with this instruction manual. [Related area: Symptoms] Skin: Rash/redness, itching Gastrointestinal: Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, stomach/abdominal bloating. Neuropsychiatric system: dizziness, insomnia, depressed mood, headache Cardiovascular: palpitations Respiratory: shortness of breath Urinary system: difficulty urinating Others: Blurred vision, ringing in the ears, swelling, numbness, back pain, excessive drop in body temperature, hot flashes on the face, abnormal glare In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately. [Symptom name: Symptom] Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur. Oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis: High fever, bloodshot eyes, mucus, sore lips, sore throat, widespread rash/redness of the skin, etc. persist or worsen rapidly. Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may appear. Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear. Aseptic meningitis: Severe headache accompanied by stiffness in the neck, fever, nausea, and vomiting appear. (Such symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.) Interstitial pneumonia: When you climb stairs or push yourself too hard, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc., which may appear suddenly or persist. Asthma: wheezing, whistling, and difficulty breathing when breathing. Blood disorders: Sore throat, fever, general malaise, whitish appearance on the face and behind the eyelids, easy bleeding (bleeding gums, nosebleeds, etc.), bruising (color that does not disappear even when pressed), etc. may appear. Digestive disorders: Black stools, hematemesis, bloody stools, mucus-bloody stools (loose stools mixed with blood, mucus, and pus), etc. may appear. Respiratory depression: Shortness of breath, difficulty breathing, etc. appear. 3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this instruction manual. Constipation, dry mouth, drowsiness 4. If your symptoms do not improve even after taking 5-6 times (especially if your fever persists for more than 3 days or occurs repeatedly), please stop taking the medicine and consult your doctor, pharmacist, or registered salesperson with this instruction manual.

[Precautions for storage and handling] (1) Store in a cool, dry place away from direct sunlight. (2) Please keep out of reach of children. (3) Do not transfer to another container. (This may cause misuse or change in quality.) (4) Do not take any medicines that have passed their expiration date.