[1st-Class OTC Drug] Loxonin S 12 tablets

●Pain relief for headache, menstrual pain (menstrual pain), toothache, pain after tooth extraction, sore throat, lumbago, arthralgia, neuralgia, muscle pain, stiff shoulder pain, earache,bruise pain, fracture pain, sprain pain, trauma pain ●Antipyretic at the time of chills and fever

Please take the following amount with water or hot water. ・Adult (15 years old and over) Dosage：1 tablet Number of doses per day：Up to 2 times. When symptoms appear, avoid taking this medicine on an empty stomach as much as possible. However, if symptoms appear again, you can take a third dose. Please allow at least 4 hours between doses. ・Under 15 Please do not take it.

Active Ingredients：1 tablet Loxoprofen sodium hydrate 68.1 mg(60 mg as anhydrate) Additives：hydroxypropylcellulose, magnesium stearate, lactose monohydrate, red ferric oxide Red spots due to additives may appear on some tablets.

Before shipment, each store's pharmacist will confirm the usability of the product. If the pharmacist determines that the product cannot be used, the order will be cancelled. Please note that due to the confirmation, your order may be delivered beyond the indicated shipping date. Also, please be sure to read the product information by yourself and accept the contents of the order before purchasing. *Please reply as soon as possible, as we will be able to ship once we receive confirmation. ＜What should be checked before purchasing this medicine? Please check the following items to make sure that you can take this product. It is known that side effects (adverse reactions to medication) may include stomach/duodenal ulcers, induction of severe asthma attacks, rashes, and swelling. For more information, please see [What caution should be taken when using this medicine?]. The following persons should not take this medicine. 〇Persons who have experienced allergic symptoms or other hypersensitive reactions to this product or the ingredients contained in this product in the past. 〇Persons who have experienced asthma after taking this medicine or other antipyretic analgesics, or cold medicine. [Persons who have experienced asthma after taking antipyretic analgesics or cold medicine containing loxoprofen sodium hydrate, aspirin (acetylsalicylic acid), aspirin aluminum, ethenzamide, ibuprofen, acetaminophen, or isopropylantipyrine.] 〇Children under the age of 15 〇Persons undergoing treatment for the following conditions at medical institutions ・Stomach / duodenal ulcers ・liver disease ・kidney disease ・heart disease 〇Persons who have been diagnosed by a doctor with the following blood abnormalities (blood diseases) ・Low red blood cell count (anemia) ・Low platelet count (difficulty in stopping bleeding, bleeds easily) ・Low white blood cell count 〇Pregnant women within 12 weeks of the expected delivery date The following persons should use caution when taking this medicine. Consult your doctor, dentist, or pharmacist before purchasing. 〇Patients undergoing medical treatment from a physician or dentist. 〇Women who are pregnant (excluding pregnant women within 12 weeks of the expected delivery date) or considered to be pregnant 〇Persons who are breastfeeding 〇Elderly people (the age of 65 or over) 〇Patients who have experienced allergic symptoms associated with drugs, etc. 〇Persons with the following diagnoses: ・Bronchial asthma ・ulcerative colitis ・Crohn's disease ・systemic lupus erythematosus ・mixed connective tissue disease 〇Persons who have ever had the following diseases: ・Stomach and duodenal ulcer ・liver disease ・kidney disease ・blood disease What should be confirmed before using this medicine? 〇This medicine is not intended to treat the disease that is causing the pain, fever, etc., but to suppress the symptoms that are occurring. Therefore, it should be taken only when symptoms are present. 〇If symptoms do not improve after 1 or 2 doses, stop taking the medicine and bring these instructions to a consultation with your doctor, dentist, or pharmacist. 〇Do not use this medicine.continuously for a long term. (If pain or other symptoms recur after 3 to 5 days of use, stop taking the medicine and seek medical attention.) 〇Do not take any of the following medicines while taking this medicine. Other antipyretic analgesics containing aspirin (acetylsalicylic acid), aspirin aluminum, ethenzamide, ibuprofen, acetaminophen and isopropylantipyrine, cold remedies and sedatives and sedatives containing allylisopropylacetylurea and bromovaleril urea, motion sickness medication [LOXONIN S PREMIUM only] 〇Do not operate vehicles or machinery after taking the medicine. (Drowsiness and other symptoms may occur.) [LOXONIN S PREMIUM only] 〇Do not drink alcohol before or after taking the medicine. [Do not take the medicine when consuming alcohol.] ＜What caution should be taken when using this medicine?＞ 〇After taking antipyretic analgesics such as this medication, symptoms such as excessive decrease in body temperature, weakness (lack of strength), and cooling of the extremities (cold hands and feet) may occur. If any of these symptoms occur, stop taking the medicine immediately and bring these instructions to your doctor or pharmacist. 〇If you experience peptic ulcers (upset stomach, heartburn, back pain) or swelling after taking this medicine, stop taking it immediately and bring these instructions to your doctor or pharmacist. In addition, in rare cases, the following severe symptoms such as gastrointestinal bleeding (vomiting blood, nausea and vomiting, abdominal pain, black tarry stools, bloody stools, etc.), gastrointestinal perforation (perforation of the gastrointestinal tract; nausea, vomiting, severe abdominal pain, etc.), and narrowing or obstruction of the small or large intestine (nausea, vomiting, abdominal pain, abdominal distention, etc.) may occur. In such cases, seek medical attention immediately. ＜What are the side effects?＞ (1) If the following symptoms occurs after using this product, you could be experiencing side effects. In such case, stop taking it immediately and bring these instructions to a consultation with your doctor or pharmacist. [Related Part：Symptoms] Skin：Rash, redness, itching Digestive organs：Abdominal pain, gastric discomfort, loss of appetite, nausea and vomiting, abdominal distention, heartburn, mouth ulcers, indigestion Circulatory organs：Increased blood pressure, palpitations Psychoneurotic systems：Drowsiness, numbness, dizziness, headache Other：Chest pain, fatigue, facial hot flashes, fever, anemia, hematuria (2) The following is a list of rare side effects that you should pay special attention to and the main subjective symptoms for each. If you experience a side effect, it is common for several of the main subjective symptoms listed for each to appear at the same time. If this happens, stop taking the medicine immediately and seek medical attention. [Symptom Names：Symptoms] Shock (anaphylaxis)：Immediately after taking the medicine, itchy skin, hives, hoarse voice, sneezing, itchy throat, breathlessness, palpitations, and confusion in consciousness may occur. Blood disorders：Sore throat, fever, general lethargy, pale face and whitish underneath the eyelids, easy bleeding (bleeding gums, nose bleeds, etc.), blue bruises (color does not disappear when pressed), etc. Mucocutaneous ocular syndrome (Stevens- Johnson syndrome), toxic epidermal necrolysis, erythema multiforme, acute generalized exanthematous pustulosis：High fever, redness of the eyes, eye discharge, sore lips, sore throat, widespread rash/redness, blisters on red areas of the skin, small pimples (small pustules) on reddened skin, general malaise, anorexia, etc. that persist or suddenly worsen. Renal impairment：Fever, rash, decreased in urine volume, general swelling, general lethargy, joint pain (pain in the joints), diarrhea, etc. Congestive heart failure：General lethargy, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc. Interstitial pneumonia：Shortness of breath or breathlessness when climbing stairs or exerting oneself a little, dry cough, fever, etc. These symptoms may appear suddenly or persist. Impairment of liver function：Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general lethargy, and loss of appetite may occur. Rhabdomyolysis：Muscle aches in limbs, shoulders, and hips; numbness, weakness, and stiffness in limbs, general lethargy, and reddish-brown urine. Aseptic meningitis：Severe headache with neck tightness, fever, nausea and vomiting may occur. (These symptoms have been reported in many patients, especially those undergoing treatment for systemic lupus erythematosus or mixed connective tissue disease.) Asthma：When you breathe, you may hear a wheezing sound or have difficulty breathing. The subjective symptoms listed above in [What caution should be taken when using this medicine?] are sorted in the following list by the location of the symptoms. If you notice any of these symptoms, please refer to the table in (2) "Side effects to especially watch out for" above. [Parts：Subjective Symptoms] Whole body：Lower than normal body temperature, lack of strength, general swelling, general swelling, fever, general lethargy, high fever, drowsiness, muscle stiffness Head：Dizziness, severe headache with neck tightness, headache, fainting Face：Face turns pale, nosebleeds, hot flashes Eyes：Whitish underneath the eyelids, yellowing of the whites of the eyes, redness of the eyes, eye discharge Ears：Tinnitus Mouth and throat：Vomiting blood, sore throat, bleeding gums, nausea, vomiting, dry cough (cough without phlegm), mouth ulcers, sores on lips and in mouth, hoarse voice, sneezing, itchy throat Chest：Heartburn, breathlessness, palpitations, shortness of breath, chest discomfort, chest pain, difficulty breathing, asthma, wheezing when breathing Abdomen：Upset stomach, abdominal pain, stomach discomfort, loss of appetite, abdominal distention, indigestion, severe abdominal pain Back：Back pain, muscle pain in shoulders, lower back, etc. Hands/Feet：Cold hands and feet, numbness, joint pain (pain in the joints), muscle pain Skin：Hives, blue bruises, rash, redness, widespread rash/redness, blisters on red areas of the skin, yellowing of the skin, itching Feces：Black tarry stools, bloody stools, diarrhea Urine：Decrease in urine volume, hematuria, brown urine, reddish brown urine Other：Increased blood pressure, bleeding easily (3) The following symptoms may appear, but if any of those symptoms persist or increase, discontinue taking the medicine and bring these instructions to a doctor or pharmacist. Dry mouth, constipation, diarrhea

(1) Store in a cool, dry place away from direct sunlight. (2) Please keep out of reach of children. (3) Please do not replace it with another container. (This may cause misuse or change in quality) (4) Do not use products whose expiration date has passed.