[Designated 2nd-Class OTC Drug] Himeros 3g

Gynomenopausal disorder, frigidity, cold sensitivity, gynecological neurasthenia

For a large dose, take 0.5g (the size of a soybean) of this drug on the tip of your finger, dissolve it well with a little water or saliva, and rub it on the mucous membrane of a woman's private parts. Use doses 1-2 times a day ＜Detailed usage instructions (recommended)＞ We recommend applying once or twice a day after cleansing your skin with a bath or shower. Please use it for 2 weeks after the end of your menstrual period, and then refrain from using it until your next menstrual period. Also, if you are postmenopausal or have not had a period for a long time due to irregular menstruation, please refrain from using it for at least 2 weeks after using it for 2 weeks. If abnormal bleeding occurs, discontinue use and consult a gynecologist.

[in 100g] Ethinyl estradiol 0.02g, estradiol 0.06g

■■Things you should not do■■ (If you do not follow these guidelines, your current symptoms may worsen or side effects may occur more easily.) 1.Do not use the following people. *(1) Persons who have had allergic symptoms due to this drug or its ingredients *(2) Before use, remove about 3 mm of this drug from the tube, mix well with 1 to 2 drops of water or hot water, and apply it to areas with thin skin such as the inner thighs to prevent drug rash, redness, itching, and swelling. People who have symptoms of *(3)Persons with thrombosis, endometriosis, stroke, heart disease, kidney disease or a history thereof *(4) People who have tumors in the breast, uterus, or ovary, or those who are at risk of having these tumors [The active ingredient of this drug may accelerate the progression of malignant tumors in the breast or uterus] (5) Persons who have a history of malignant tumor in their family or themselves *(6) Persons with uterine fibroids, diabetes, hypertension, epilepsy, or liver dysfunction (7) People who are menstruating, have abnormal vaginal bleeding, or have vaginal discharge. (8) Pregnant women or women who may be pregnant, breastfeeding women (9)Children 2.Do not use on the following areas. (1)Eyes and around the eyes *(2) Affected areas with severe trauma, eczema, sores, inflammation, and suppuration 3.Do not use any of the following medicines while using this drug. Other medicines containing the same ingredients 4.Do not consume any of the following foods while using this drug. Foods containing St. John's wort, ipriflavone 5. Do not let it get on anyone other than the user. (1) Wash your hands thoroughly with soap and lukewarm water after use. (2) Be careful not to let this agent come into contact with anyone other than the user. If it gets on your skin, wash it off immediately. (3) If the applied area may come into contact with other people, wash the applied area thoroughly with soap and lukewarm water. 6.Do not use for contraceptive purposes. (1) If you wish to use contraception, we strongly request that you take appropriate measures. (2) Use of this drug may change your menstrual cycle, so please refrain from using contraceptive methods that rely on regular menstrual cycles or basal body temperature, such as the Ogino method. ■■Things to consult■■ 1. The following people should consult a doctor, pharmacist, or registered seller before use. (1)Person receiving treatment from a doctor (2) Persons who have had allergic symptoms (rash, redness, itching, rash, swelling, etc.) due to drugs, etc. 2. If the following symptoms appear after use, it may be a side effect, so please stop using it immediately and consult your doctor, pharmacist, or registered salesperson with this document. [Related area: Symptoms] Skin: Rash/redness, itching, rash, swelling Breasts: pain, engorgement Gastrointestinal: Nausea, vomiting, loss of appetite Other: Headache, swelling, dizziness 3. If your menstrual cycle or menstrual blood changes significantly, stop using the product immediately and consult your doctor, pharmacist, or registered salesperson with this document in hand. 4. If your symptoms do not improve after using this product for about 2 weeks, please consult your doctor, pharmacist, or registered salesperson with this document. 5. If you use the product incorrectly, stop using it immediately and consult your doctor, pharmacist, or registered seller with this document. ■■Other notes■■ Before using this drug for the first time, we recommend a breast and uterine examination. In addition, after starting use, please have regular breast and uterine examinations.

■■Precautions for storage and handling■■ 1. Store tightly closed in a cool, dry place away from direct sunlight. 2. Please keep out of reach of children. 3.Do not transfer to other containers. (This may cause misuse or change in quality.) 4.Do not use products that have passed their expiration date. *5. Do not touch your eyes or mucous membranes (excluding the inside of your vagina) with your hands covered with this drug. 6. If you dispense too much of this drug, do not return it to the tube. 7. After use, make sure that this agent does not adhere to the threaded part of the tube or the threaded part of the cap side. If it does, wipe it clean. then close the cap. ■■Other■■ This drug uses a large container compared to its contents in order to display the legal labeling. Therefore, there is a gap inside the container, but to maintain quality, we fill it with nitrogen gas and strictly control the content.