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[2024 Latest] Comprehensive Guide to Japan's Popular Cold Medicine Lulu and Its Effects

For those seeking optimal care tailored to cold symptoms. Lulu provides a wide range of products addressing sore throat, fever, runny nose, and cough, offering reassurance for the whole family. With effective ingredients, Lulu ensures thorough cold care.

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Table of Contents

What is Lulu?

Lulu is a comprehensive cold medicine series designed to address various symptoms associated with colds and influenza. It offers multiple product lines, allowing users to choose the most suitable product for their specific symptoms, making it a widely used household medicine. Additionally, the Lulu series includes products that are suitable for children aged 7 and older as well as adults, providing a lineup that supports the health of the entire family.

What are the main ingredients of Lulu?

Key ingredients in the Lulu series include acetaminophen (antipyretic and analgesic), tranexamic acid (anti-inflammatory), clemastine fumarate (anti-allergic), and belladonna total alkaloids (runny nose suppressant). These ingredients work in combination to effectively address major cold symptoms such as fever, sore throat, runny nose, nasal congestion, cough, and phlegm.

What are the main effects of Lulu?

Lulu is designed to quickly alleviate cold symptoms. For instance, acetaminophen reduces fever and pain, bromhexine hydrochloride helps expel phlegm, and clemastine fumarate alleviates allergic symptoms. This combination reduces discomfort caused by colds and supports faster recovery.

Reasons for Lulu's Popularity

  1. Extensive Product Lineup: Lulu offers a diverse range of products to address various cold symptoms. With products targeting runny nose, nasal congestion, sore throat, and cough, it provides tailored care for different situations.
  2. Effective Ingredients: Lulu products are balanced with active ingredients to alleviate cold symptoms. This ensures comprehensive care according to individual symptoms.
  3. Formulation for 11 Cold Symptoms: The Lulu series includes numerous active ingredients to address 11 types of cold symptoms. It provides holistic care for symptoms such as runny nose, cough, fever, and sore throat with a single medication.

Lulu Product Comparison Table

Product Name Product Image Ingredients
New Lulu A Gold DXα New Lulu A Gold DXα Clemastine fumarate, belladonna total alkaloids, bromhexine hydrochloride, tranexamic acid, acetaminophen, dl-methylephedrine hydrochloride, dextromethorphan hydrobromide hydrate, anhydrous caffeine
New Lulu A Gold S New Lulu A Gold S Clemastine fumarate, belladonna total alkaloids, bromhexine hydrochloride, acetaminophen, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, anhydrous caffeine, benfotiamine
New Lulu-A Tablets New Lulu-A Tablets Acetaminophen, clemastine fumarate, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, potassium guaiacol sulfonate, anhydrous caffeine, benfotiamine
Daiichi Sankyo Lulu Attack EX Premium Sore Throat Cold Medicine Daiichi Sankyo Lulu Attack EX Premium Sore Throat Cold Medicine Ibuprofen, tranexamic acid, d-chlorpheniramine maleate, dl-methylephedrine hydrochloride, dihydrocodeine phosphate, anhydrous caffeine, benfotiamine, riboflavin
Daiichi Sankyo Comprehensive Cold Medicine Lulu Attack NX Daiichi Sankyo Comprehensive Cold Medicine Lulu Attack NX Ibuprofen, tranexamic acid, isopropamide iodide, d-chlorpheniramine maleate, dihydrocodeine phosphate, dl-methylephedrine hydrochloride, anhydrous caffeine, riboflavin, hesperidin
Lulu Attack EX Lulu Attack EX Tranexamic acid, ibuprofen, clemastine fumarate, bromhexine hydrochloride, dl-methylephedrine hydrochloride, dihydrocodeine phosphate, thiamine nitrate, riboflavin
Daiichi Sankyo Lulu Attack CX Cough Comprehensive Cold Medicine Daiichi Sankyo Lulu Attack CX Cough Comprehensive Cold Medicine Ibuprofen, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, L-carbocisteine, glycyrrhizic acid, d-chlorpheniramine maleate, anhydrous caffeine, benfotiamine
Lulu Attack FXα Lulu Attack FXα Isopropylantipyrine, acetaminophen, ginger powder, clemastine fumarate, glycyrrhizic acid, tipepidine hibenzate, noscapine, dl-methylephedrine hydrochloride, anhydrous caffeine, ascorbic acid
Daiichi Sankyo LULU Oral Solution Ma Huang Tang Bottles Daiichi Sankyo LULU Oral Solution Ma Huang Tang Bottles Ephedra, apricot kernel, cinnamon bark, licorice
Lulu Medical Drop Honey Lemon Flavor Lulu Medical Drop Honey Lemon Flavor dl-methylephedrine hydrochloride, potassium guaiacol sulfonate, cetylpyridinium chloride hydrate
Lulu Medical Drop Grape Flavor Lulu Medical Drop Grape Flavor dl-methylephedrine hydrochloride, potassium guaiacol sulfonate, cetylpyridinium chloride hydrate
Daiichi Sankyo LULU Sore Throat Spray Daiichi Sankyo LULU Sore Throat Spray Sodium azulene sulfonate hydrate
Daiichi Sankyo New LULU Nasal Spray Daiichi Sankyo New LULU Nasal Spray Naphazoline hydrochloride, chlorpheniramine maleate, lidocaine hydrochloride, benzethonium chloride
Lulu Nourishing Liquid Lulu Nourishing Liquid Ginseng extract, royal jelly extract, ginger extract, angelica extract, benfotiamine (vitamin B1 derivative), vitamin B2 phosphate ester, vitamin B6, nicotinamide
Lulu Nourishing Liquid DX Lulu Nourishing Liquid DX Ginseng extract, royal jelly extract, ginger extract, jujube extract, benfotiamine (vitamin B1 derivative), vitamin B2 phosphate ester, vitamin B6, nicotinamide

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Ingredients and Effects

Ingredient Name Description
Clemastine fumarate Antihistamine effects used to alleviate allergic symptoms and runny nose.
Belladonna total alkaloids Acts on the autonomic nervous system to relieve digestive symptoms.
Bromhexine hydrochloride Improves bronchial symptoms by thinning phlegm.
Tranexamic acid Anti-inflammatory properties to ease sore throat and swelling.
Acetaminophen Antipyretic and analgesic effects to relieve fever and headache.
dl-Methylephedrine hydrochloride Expands the bronchi to reduce coughing and wheezing.
Dextromethorphan hydrobromide hydrate Suppresses cough, particularly effective for nighttime coughing.
Anhydrous caffeine Stimulates the central nervous system, reducing fatigue.
Dihydrocodeine phosphate Effective in suppressing cough.
Noscapine A strong antitussive agent to suppress cough.
Potassium guaiacol sulfonate Helps dissolve and expel phlegm.
Ibuprofen Reduces inflammation, alleviating pain and fever.
d-Chlorpheniramine maleate Reduces allergy responses, alleviating sneezing and runny nose.
Isopropamide iodide Reduces excessive gastrointestinal secretion to relieve digestive symptoms.
Riboflavin Supports energy metabolism in the body and overall health.
Hesperidin Strengthens capillaries and promotes blood circulation.
Thiamine nitrate Vitamin B1 that supports energy metabolism.
L-Carbocisteine Softens mucus, making it easier to expel phlegm.
Glycyrrhizic acid Anti-inflammatory effects that alleviate swelling and throat pain.
Isopropylantipyrine Antipyretic and analgesic effects to relieve headache and joint pain.
Ginger powder Suppresses cough and reduces bronchial inflammation.
Tipepidine hibenzate An antitussive and expectorant medication.
Ascorbic acid Supports immunity and helps prevent colds.
Ephedra A traditional herbal component that alleviates early cold symptoms.
Apricot kernel Suppresses cough and makes it easier to expel phlegm.
Cinnamon bark Warms the body and promotes blood circulation.
Licorice Reduces inflammation, easing throat swelling and pain.
Cetylpyridinium chloride hydrate Antiseptic properties to alleviate oral and throat inflammation.
Sodium azulene sulfonate hydrate Reduces inflammation, relieving swelling and throat pain.
Naphazoline hydrochloride Constricts nasal mucosa to relieve nasal congestion.
Chlorpheniramine maleate Antiallergic effects to alleviate runny nose and sneezing.
Lidocaine hydrochloride Local anesthetic properties to relieve pain.
Benzethonium chloride Antibacterial properties to prevent infections.
Ginseng extract Tonic effects that aid in recovery from fatigue.
Royal jelly extract Provides nutritional support and boosts immunity.
Ginger extract Promotes blood circulation and has anti-inflammatory effects.
Angelica extract Improves circulation and reduces fatigue and cold sensitivity.
Jujube extract Promotes energy metabolism and supports health.
Vitamin B2 phosphate ester Supports metabolism and maintains normal nerve function.
Vitamin B6 Aids in energy metabolism and reduces fatigue.
Nicotinamide A type of vitamin B3 that supports energy production.
Benfotiamine (Vitamin B1 derivative) A highly absorbable form of vitamin B1 that supports nerve protection and energy metabolism.

Lulu Product Introduction

Introduction to the pharmaceutical classification, effects, and usage age of each product.

Comprehensive Cold Medicine

New Lulu A Gold DXα

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (sore throat, fever, runny nose, nasal congestion, cough, phlegm, chills, headache, sneezing, joint pain, muscle pain).
  • Usable Age: 7 years and older
  • Main Ingredients: Clemastine fumarate, belladonna total alkaloids, bromhexine hydrochloride, tranexamic acid, acetaminophen, dl-methylephedrine hydrochloride, dextromethorphan hydrobromide hydrate, anhydrous caffeine.
  • Usage Frequency: 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, excitement, seizures, headache, shortness of breath, difficulty urinating, excessive drop in body temperature, facial flushing, unusual light sensitivity.

New Lulu A Gold S

  • Pharmaceutical Classification: Category 2 over-the-counter drug
  • Effects and Efficacy: Relieves cold symptoms (runny nose, nasal congestion, fever, sore throat, cough, phlegm, sneezing, chills, headache, joint pain, muscle pain).
  • Usable Age: 12 years and older
  • Main Ingredients: Clemastine fumarate, belladonna total alkaloids, bromhexine hydrochloride, acetaminophen, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, anhydrous caffeine, benfotiamine (Vitamin B1 derivative).
  • Usage Frequency: 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, headache, excitement, seizures, difficulty urinating, facial flushing, unusual light sensitivity, excessive drop in body temperature.

New Lulu-A Tablets

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (runny nose, nasal congestion, sneezing, sore throat, cough, phlegm, chills, fever, headache, joint pain, muscle pain).
  • Usable Age: 12 years and older
  • Main Ingredients: Acetaminophen, clemastine fumarate, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, potassium guaiacol sulfonate, anhydrous caffeine, benfotiamine (Vitamin B1 derivative).
  • Usage Frequency: 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, excitement, seizures, difficulty urinating, excessive drop in body temperature.

Daiichi Sankyo Lulu Attack EX Premium Sore Throat Cold Medicine

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (sore throat, fever, chills, headache, runny nose, nasal congestion, sneezing, cough, phlegm, joint pain, muscle pain).
  • Usable Age: 15 years and older
  • Main Ingredients: Ibuprofen, tranexamic acid, d-chlorpheniramine maleate, dl-methylephedrine hydrochloride, dihydrocodeine phosphate, anhydrous caffeine, benfotiamine (Vitamin B1 derivative), riboflavin (Vitamin B2).
  • Usage Frequency: 3 tablets per dose, 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, gastric discomfort, dizziness, insomnia, palpitations, shortness of breath, difficulty urinating, blurred vision, tinnitus, swelling, nosebleeds, gum bleeding, prolonged bleeding, back pain, fatigue.

Daiichi Sankyo Comprehensive Cold Medicine Lulu Attack NX

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (runny nose, nasal congestion, sore throat, cough, phlegm, fever, chills, sneezing, headache, joint pain, muscle pain).
  • Usable Age: 15 years and older
  • Main Ingredients: Ibuprofen, tranexamic acid, isopropamide iodide, d-chlorpheniramine maleate, dihydrocodeine phosphate, dl-methylephedrine hydrochloride, anhydrous caffeine, riboflavin (Vitamin B2), hesperidin.
  • Usage Frequency: 2 tablets per dose, 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, gastric discomfort, dizziness, headache, palpitations, shortness of breath, difficulty urinating, blurred vision, tinnitus, swelling, nosebleeds, gum bleeding, prolonged bleeding, back pain, fatigue, facial flushing, unusual light sensitivity.

Lulu Attack EX

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (sore throat, fever, chills, headache, runny nose, nasal congestion, sneezing, cough, phlegm, joint pain, muscle pain).
  • Usable Age: 15 years and older
  • Main Ingredients: Tranexamic acid, ibuprofen, clemastine fumarate, bromhexine hydrochloride, dl-methylephedrine hydrochloride, dihydrocodeine phosphate, thiamine nitrate (Vitamin B1 nitrate), riboflavin (Vitamin B2).
  • Usage Frequency: 2 tablets per dose, 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, headache, difficulty urinating, excessive drop in body temperature.

Daiichi Sankyo Lulu Attack CX Cough Comprehensive Cold Medicine

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (cough, phlegm, sore throat, runny nose, nasal congestion, fever, chills, sneezing, headache, joint pain, muscle pain).
  • Usable Age: 15 years and older
  • Main Ingredients: Ibuprofen, dihydrocodeine phosphate, noscapine, dl-methylephedrine hydrochloride, L-carbocisteine, glycyrrhizic acid, d-chlorpheniramine maleate, anhydrous caffeine, benfotiamine.
  • Usage Frequency: 2 tablets per dose, 3 times a day, preferably within 30 minutes after meals.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, gastric discomfort, dizziness, palpitations, shortness of breath, difficulty urinating, blurred vision, tinnitus, swelling, nosebleeds, gum bleeding, prolonged bleeding, back pain, excessive drop in body temperature, fatigue.

Lulu Attack FXα

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves cold symptoms (fever, chills, headache, sore throat, runny nose, nasal congestion, cough, phlegm, joint pain, muscle pain, sneezing).
  • Usable Age: 7 years and older
  • Main Ingredients: Isopropylantipyrine, acetaminophen, ginger powder, clemastine fumarate, glycyrrhizic acid, tipepidine hibenzate, noscapine, dl-methylephedrine hydrochloride, anhydrous caffeine, ascorbic acid.
  • Usage Frequency: 2 tablets per dose, 3 times a day (for ages 15 and older); 1 tablet per dose, 3 times a day (for ages 7 to 15).
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, excitement, seizures, difficulty urinating, excessive drop in body temperature.

Ma Huang Tang

Daiichi Sankyo LULU Oral Solution Ma Huang Tang Bottles

  • Pharmaceutical Classification: Class 2 drug
  • Effects and Efficacy: For individuals with robust physical strength and early cold symptoms including chills, fever, headache, cough, joint pain, and no sweating. Relieves common cold, nasal cold, bronchitis, and nasal congestion.
  • Usable Age: 15 years and older
  • Main Ingredients: Ma Huang Tang extract (extracted from ephedra, apricot kernel, cinnamon bark, licorice).
  • Usage Frequency: 1 bottle per dose, 3 times a day, between meals.
  • Side Effects: Rash, redness, itching, nausea, loss of appetite, gastric discomfort, excessive sweating, general weakness. Rare cases may develop pseudoaldosteronism or myopathy.

Cough Suppressants and Expectorants

Lulu Medical Drop Honey Lemon Flavor

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves throat inflammation-related pain, swelling, roughness, discomfort, hoarseness, cough, phlegm, and wheezing (wheezy or whistling cough).
  • Usable Age: 5 years and older
  • Main Ingredients: dl-Methylephedrine hydrochloride, potassium guaiacol sulfonate, cetylpyridinium chloride hydrate.
  • Usage Frequency: For ages 15 and older: 2 drops per dose; for ages 5 to 11: 1 drop per dose. 5-6 times daily, with at least a 2-hour interval between doses.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, and other symptoms may occur.

Lulu Medical Drop Grape Flavor

  • Pharmaceutical Classification: Des. 2nd-Class OTC Drug
  • Effects and Efficacy: Relieves throat inflammation-related pain, swelling, roughness, discomfort, hoarseness, cough, phlegm, and wheezing (wheezy or whistling cough).
  • Usable Age: 5 years and older
  • Main Ingredients: dl-Methylephedrine hydrochloride, potassium guaiacol sulfonate, cetylpyridinium chloride hydrate.
  • Usage Frequency: 5-6 times daily with at least a 2-hour interval between doses.
  • Side Effects: Rash, redness, itching, nausea, vomiting, loss of appetite, dizziness, and other symptoms may occur.

Oral Anti-inflammatory Medication

Daiichi Sankyo LULU Sore Throat Spray

  • Pharmaceutical Classification: Class 3 drug
  • Effects and Efficacy: Relieves throat inflammation-related pain, swelling, discomfort, roughness, hoarseness, and oral ulcers.
  • Usable Age: No restrictions (children should use under parental guidance).
  • Main Ingredients: Sodium azulene sulfonate hydrate.
  • Usage Frequency: Spray an appropriate amount onto the affected area several times a day.
  • Side Effects: Rash, redness, itching, or irritation in the oral cavity may occur.

Nasal Spray

Daiichi Sankyo New LULU Nasal Spray

  • Pharmaceutical Classification: Class 2 drug
  • Effects and Efficacy: Alleviates symptoms of acute rhinitis, allergic rhinitis, and sinusitis, including runny nose, nasal congestion, sneezing, and head heaviness.
  • Usable Age: 15 years and older
  • Main Ingredients: Naphazoline hydrochloride, chlorpheniramine maleate, lidocaine hydrochloride, benzethonium chloride.
  • Usage Frequency: Spray 1-2 times into each nostril, up to 6 times daily, at 3-4 hour intervals.
  • Side Effects: Rash, redness, itching, nasal swelling, irritation, and rarely, shock (anaphylaxis) may occur.

Vitamin-containing Health Supplements

Lulu Nourishing Liquid

  • Pharmaceutical Classification: Quasi-drug
  • Effects and Efficacy: Nutritional supplementation in cases of febrile consumptive diseases, recovery from illness, loss of appetite, physical fatigue, nutritional disorders, pre- and postpartum conditions. Supports weak constitutions and acts as a tonic.
  • Usable Age: 15 years and older
  • Main Ingredients: Ginseng extract, royal jelly extract, ginger extract, angelica extract, benfotiamine (Vitamin B1 derivative), Vitamin B2 phosphate ester, Vitamin B6, nicotinamide.
  • Usage Frequency: 1 bottle (30mL) per day.
  • Side Effects: Rash, gastric discomfort, or diarrhea may occur.

Lulu Nourishing Liquid DX

  • Pharmaceutical Classification: Quasi-drug
  • Effects and Efficacy: Provides nutritional supplementation for febrile consumptive diseases, recovery from illness, loss of appetite, physical fatigue, nutritional disorders, and pre- and postpartum conditions. Supports weak constitutions and acts as a tonic.
  • Usable Age: 15 years and older
  • Main Ingredients: Ginseng extract, royal jelly extract, ginger extract, jujube extract, benfotiamine (Vitamin B1 derivative), Vitamin B2 phosphate ester, Vitamin B6, nicotinamide.
  • Usage Frequency: 1 bottle (30mL) per day.
  • Side Effects: Rash, gastric discomfort, or diarrhea may occur.

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Precautions for Use

  • Ensure to strictly follow the dosage and instructions provided in the accompanying manual.
  • For children, use under parental supervision and adhere to the manual's specified dosage and instructions.
  • If symptoms do not improve, consult a medical institution promptly.

About Product Information

DOKODEMO strives to display the latest product information on its website; however, product specifications and styles (capacity, packaging, ingredients, country of origin, etc.) may change due to manufacturer circumstances. The actual delivered product's information may differ from the website. Please check the label and precautions of the delivered product before use.

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